• BPRSJ338: Therapeutic Applications for COVID-19

      Precision Health Ecosystem FutureTech BPRSJ338: Therapeutic Applications for COVID-19

      BPRSJ338 exhibits high potency of anti-SARS-CoV-2 activity and is in development for fighting COVID-19 as a first-in-class drug. BPRSJ338 also potently inhibits against broad-spectrum coronaviruses including SARS-CoV-2, SARS-CoV, HCoV-229E, HCoV-OC43, TGEV, FIPV and MHV. Related US and Taiwan patents have been granted.​ Therefore it is also applicable to fight against severe evolving coronaviruses in the future.
    • Heterocyclic compounds and use thereof

      Precision Health Ecosystem FutureTech Heterocyclic compounds and use thereof

      In this technology, a series of potent MOR/NOP agonists has been developed, which demonstrated potent antinociception in tail flick and cancer pain mouse models with fewer side-effects in respiratory suppression, heart rate decreasing, and constipation models than morphine.
    • The comprehensive multi-tier long-term care delivery information platform

      Precision Health Ecosystem FutureTech The comprehensive multi-tier long-term care delivery information platform

      This project aims to incorporate the state-of-the-art InformationCommunication Technologies (ICT), the Internet of Things (IoT), Big Data techniques in linking every aspect of community-based integrated long-term care (LTC), improving the efficiency of care servicesadministrative process,to realize the idea of Aging in Place emphasized in the Long-term Care Policy 2.0 in Taiwan.
    • Intelligent Scalp Detection System

      Precision Health Ecosystem FutureTech Intelligent Scalp Detection System

      This system uses the innovative AIoT application to target annoying scalp maintenance problemsdevelops an intelligent scalp detectionmanagement system. The core of the technology is to use deep learning-based object detection models. Tens of thousands of microscopic image data sets that are labeledtrained for scalp symptoms. As a result, the scalp image recognition module is develop, such as dandruff, hair loss, oil, and inflammation, etc. Hence this system can provide scalp detection, and maintenance effectiveness tracking functions lead scalp maintenance services to a new level of intelligent management.
    • Wearable ultrasound device for diagnosis of sleep apnea

      Precision Health Ecosystem FutureTech Wearable ultrasound device for diagnosis of sleep apnea

      We developed a wearable ultrasound monitoring device to monitor the collapse of tongue roots of sleep respiratory patients throughout the night,completed clinical trials in the sleep center. The experimental results show that this device can effectively monitor OSA. The tongue structure changes at the timeintegrates ultrasound information into the commercial PSG system. It is expected
    • High-value recycling waste materials to produce lightweight aggregate

      Smart machinerynovel materials FutureTech High-value recycling waste materials to produce lightweight aggregate

      Responding the government’s policy of “circular economy”. The project is to manufacture high value and energy saving construction material (lightweight aggregate) by using Taiwan environmental and industrial waste, such as paper sludge, textile sludge, organic waste solvent from semiconductor industry, and reservoir sludge, etc. Based on fully recyclable concept to create real benefits for domestic ecological environment.
    • Cisd2 activators: Novel therapeutics for non-alcoholic fatty liver diseases (NAFLD) and steatohepatitis (NASH)

      Precision Health Ecosystem FutureTech Cisd2 activators: Novel therapeutics for non-alcoholic fatty liver diseases (NAFLD) and steatohepatitis (NASH)

      Our previous studies suggested that increase Cisd2 levels may attenuate the pathogenesis of NAFLD/NASH. Accordingly, potent Cisd2 activators with the capacity to enhance Cisd2 levels were identified through the screening of skeletally diverse collections and structural optimization. So far BPRCD0001S0 is the most potent Cisd2 activator obtained, which has been studied extensively. Data obtained revealed that BPRCD0001S0 has no detectable toxicity in vivo, can activate Cisd2 in liver and ameliorate obese-related and fructose-induced NAFLD/NASH.
    • Harmoscope

      Precision Health Ecosystem FutureTech Harmoscope

      Harmoscope is a virtual biopsy technology for dermatology. The superior performances of in vivo Harmoscope has been clinically validated by NTU hospital for 14 years, with the deepest penetration, super-resolution,the highest contrast all at the same time. Without imaging processinglabeling, Harmoscope raw images provide the same level of resolutioninformation as the time-consuming gold standard H&E histopathology, allowing dermatologists and pathologists to grade and classify various skin lesions for immediate therapeutic decision without physical biopsy. This award-winning technology will release the saturated loading of skin biopsy examination, greatly improve the quality of point of care, while providing a trauma-free real-time alternative for skin lesion patients.
    • A Non-Invasive AI Imaging Technique for Quick Risk Assessment of Stroke and Cardiovascular Diseases

      Precision Health Ecosystem FutureTech A Non-Invasive AI Imaging Technique for Quick Risk Assessment of Stroke and Cardiovascular Diseases

      This product is a novel risk assessment tool for carotid artery stenosis and stroke. This is a revolutionary healthcare technology using motion analysis and quantification to extract information from pulses for risk assessments. The entire process is completed by taking a short video clip aimed at the neck with only one simple click on any mobile devices or our apparatus, anywhere, anytime. In less than five minutes, the user receives an evaluation report indicating low to high stroke risk. Our product accuracy stands higher than 90% when compared to the clinical outcome. The future indications of this product can be extended to arrhythmia, venous fistula obstruction, etc. This product has the great potential to achieve our dream of “personalized mobile hospital” in the future world.
    • A Badminton Training and Activities Recognition System

      AI & IOT Application FutureTech A Badminton Training and Activities Recognition System

      The system consists of a racket sensor, a smartphone App, and the IoT shuttlecock serving machines. Data of the 3-axis inertial sensor will be sent to the smartphone via Bluetooth for analysis. The App can recognize 7 stroke activities, including clear, cut, drive, lob, rush, net play, and smash using machine learning algorithms, while the speed, force, and stroke times are recorded at the same time. The App also enables the user to set parameters of the serving machines for assigning shot placements and serving schedules.
    • 3D Object Referring and Grasp Detection Networks

      AI & IOT Application FutureTech 3D Object Referring and Grasp Detection Networks

      "It is expected that human will work with robots in the coming years. However, it is still unknown how both can collaborate together. Meanwhile, it is still very time-consuming to deploy intelligent robots in production lines. For this work, we investigate deep comprehension for 3D (point cloud)text (voice) signals to enable novel human-robotic object referring for robotic arms. For the task
    • KarmaZone Strike Zone3D Markerless Motion Analysis System

      AI & IOT Application FutureTech KarmaZone Strike Zone3D Markerless Motion Analysis System

      Six synchronized high-speed cameras were installed in the baseball stadium in NTUS. We established the calibration equation of the multi-camera systemestablished an electronic strike zone system, KarmaZone, that can automatically coordinates when the pitch crossed the home plate. From the slow motion videos recorded, the markerless 3D human posture estimation has been developed with the deep
    • Dual-Core Self-Centering Energy Dissipation Brace

      Smart machinerynovel materials FutureTech Dual-Core Self-Centering Energy Dissipation Brace

      Conventional buildings use beambrace members to dissipate seismic energy. However, these members may cause residual deformation of buildings under large earthquakes, which affects the building seismic performanceincreases the difficulty of reuse after earthquakes. Therefore, a novel earthquake-resisting member "Dual-Core Self-Centering Brace, DC-SCB” was developed. The DC-SCB uses tendons to provide the elastic restoring forcea friction devicesteel bars to provide energy dissipation so that the building can return to the original position after major earthquakes. The DC-SCB significantly reduces the residual deformationrepair cost of the building after earthquakes, also reducing the large lateral displacementcollapse of the building.
    • AS2 3D

      Electronic & Optoelectronics FutureTech AS2 3D

      We developed a Multiview 3D capturing system based on camera array for generating stereoscopic 3D printing. Based on the framework, we are capable to create well aligned 3D contentcalibrated color images. The depth perception of content can be manually adjusted for preview,for generating quality 3D stereoscopic printing.
    • Building A Deep Learning-based Chest X-ray CADe Platform MedCheX

      Precision Health Ecosystem FutureTech Building A Deep Learning-based Chest X-ray CADe Platform MedCheX

      As we continue to face the rapid increase in confirmed Coronavirus cases around the world, we created an AI-based pneumonia detection platform for COVID-19. The system is able to automatically detect high-risk patients with pneumonia that will then send information to doctors. With that information, the doctors are then able to make follow-up decisions and provide a treatment plan after the diagnosis. In specific, doctors from the Department of Medical Imaging provided us thousands of positive and negative chest x-rays for pneumonia as a training set. Our system has already been tested with and adopted by doctors at the NCKU Hospital. The system achieved 95% accuracy to detect the pneumonia symptom, based on 1400 test images.
    • A Novel “Platform Technology” in Surgical Hemostasis

      Precision Health Ecosystem FutureTech A Novel “Platform Technology” in Surgical Hemostasis

      A novel “Platform Technology” in surgical hemostasis, based on biodegradable polyurethane particles with anti-inflammatory and nerve repair, not only accelerates wound healing but also provides solutions for hemostasis during surgery, and improve biocompatibility and adverse of commercially hemostats to achieve the best patient care. Our first product is aimed to provide a hemostatic agent, use on the bleeding surface and deep, with additional functions to surgeons, which allows customers to shorten the operation time, reduce stay in the hospital, and reduce the chance of secondary surgery.
    • Highly Efficient Quantum Key Distribution

      Excellence Research Center FutureTech Highly Efficient Quantum Key Distribution

      Quantum key distribution exploits the transmissiondetection of single photons’ quantum states to generatedistribute secure keys, allowing absolutely secure communication. We use a self-developed miniature single-photon source, together with the single-photon wavepacket engineering, to implement a highly efficient protocol of differential-phase-shift quantum key distribution. Using the Ca
    • Real time wireless diagnostic system

      Precision Health Ecosystem FutureTech Real time wireless diagnostic system

      "PressureDOT team will develop the first intra-abdominal pressure monitoringlocalization micro internet device of things, to integrate into critical care vital sign monitoring systemtake care of the critical patients. This will ensure our role in the marketset up market barrier in this type of medical devices. With this platform, we can collect the continuous physical signal from c
    • Breakthroughsachievements of key technologies of six-axis force/torque sensor

      Smart machinerynovel materials FutureTech Breakthroughsachievements of key technologies of six-axis force/torque sensor

      Multi-axis force/torque sensors are key components of precision machinesrobot arms. Development of the multi-axis force/torque sensor is a popular research topic in Taiwan. This research developed design methods, calibration machinescalibration algorithms for multi-axis force/torque sensors. These efforts contribute the enhancement of precision of 0.20 (1.25 times than commercialize pro
    • Using Herbmedotcin technology to solve the antibiotic abuse problem

      Precision Health Ecosystem FutureTech Using Herbmedotcin technology to solve the antibiotic abuse problem

      The "Herbmedotcin" technology platform is a major breakthrough in the several thousand years history of herbal medicine knowledge. Use patented technology to find potential natural functional molecules, with appropriate additivesoptimal processing conditions, to achieve a significant increase in their efficacy. This technology is also known as "molecular herbology". They h
    • Antimicrobial peptide Epinecidin-1 promotes complete skin regeneration of methicillin-resistant Staphylococcus aureus-infected burn wounds in a swine model

      Precision Health Ecosystem FutureTech Antimicrobial peptide Epinecidin-1 promotes complete skin regeneration of methicillin-resistant Staphylococcus aureus-infected burn wounds in a swine model

      Chronic wound infection is a leading cause of mortality in injured patients worldwide. At present, available systemic antibiotic treatments have an insufficient tissue penetration ability and allow the development of antibiotic-resistant pathogens. The identification of therapeutic agents with wound healing and antimicrobial functions is necessary to heal the wound and cure infections. Our report shows that the antimicrobial peptide (AMP) Epinecidin-1 (Epi-1) efficiently heals MRSA-infected heat burn injuries and provides protection from infection in mouse and pig model. Our results demonstrate that the biomaterial Epi-1 heals wounds through increasing epithelial cell proliferation, vascularization, and the formation of collagen and controls MRSA infection-mediated sepsis in pigs.
    • Building energy conversionventilation device

      Smart machinerynovel materials FutureTech Building energy conversionventilation device

      The present invention relates to a building natural energy conversion ventilation device, which has cleaning indoor and outdoor air, also has air-conditioning cooling heating supplies, which can make the intake air closer to the dew point temperature of the indoor side air after heat exchange, thereby reducing the heat load of the heat source unit, Enhance its operating efficiency, achieve energy saving avoid waste heat emission.
    • A High Frequency Ventilator and Electrical Impedance Tomography for Respiratory Treatment

      Precision Health Ecosystem FutureTech A High Frequency Ventilator and Electrical Impedance Tomography for Respiratory Treatment

      The high-frequency jet ventilator uses the solenoid valve and feedback techniques to control the operational parameters of the ventilator. The proposed dual-mode control mechanism allows dynamic adjustment of the tidal volume, pressure, and duration of ventilation simultaneously. The system has been verified in animal experiments and demonstrated a significant improvement in the gas exchange efficiency. Besides, the bioelectrical impedance measurement can provide real-time and accurate regional information of the lungs, which helps to monitor the patient’s condition during respiratory treatment. This work also adopts wireless communication and remote-control technology to reduce the risk of infection of medical professionals.
    • Air-stable luminescent organic-inorganic perovskite nanocrystal-polymer composites

      Smart machinerynovel materials FutureTech Air-stable luminescent organic-inorganic perovskite nanocrystal-polymer composites

      The technology realizes a perovskite nanocrystal-polymer composite material, which has extremely high stability at room temperaturehigh temperature. It can be used for 3D printing, shaped into fluorescent microfilaments,can also be used for white light-emitting diodes. The application of this air-stabile perovskite nanocrystal-polymer composite material in the 3D printing industry, texti
    • Infectious Disease Diagnosis and Water Quality Monitoring Using Nanomaterials Immobilized Paper and a Flow Controllable Microfluidic Device

      Precision Health Ecosystem FutureTech Infectious Disease Diagnosis and Water Quality Monitoring Using Nanomaterials Immobilized Paper and a Flow Controllable Microfluidic Device

      Here we present a portable microfluidic device that can perform immunoassay for infectious disease diagnosis or detect heavy metal ions in water samples. The device is composed of two major components: nanomaterials modified paper-based detection platform and semi-automated flow manipulator. A reusable 3D-printed device is used to hold a disposable detection pad that modified with functional nanomaterials for water quality monitoring or antibodies for disease diagnosis. Besides, the use of spring-containing 3D-printed syringes manipulates a large-volume sample without manual actuation. Meanwhile, by controlling the flow rate via the linked flow regulator at the syringe outlet, solutions can react stably with the paper platform, which provides detection and pre-concentration effects.
    • Low-Temperature Defects Elimination Technology for Semiconductor devices

      Electronic & Optoelectronics FutureTech Low-Temperature Defects Elimination Technology for Semiconductor devices

      The low-temperature defect passivation technology developed by our team can effectively eliminate defects in materials under 250°C, and leads to the improvement of the performance and reliability of devices. The technology has demonstrated the significant performance improvement when applying on GaN-based devices. After the treatment, the conducting current of FET devices is increased with the same operation condition. Moreover, in terms of LED devices, the emission efficiency was enhanced and the forward operating voltage decreased as well.
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