進階篩選

Technical category
技術研發單位
    • 變種冠狀病毒蛋白晶片:疫情與後疫情時代之應用

      Precision Health Ecosystem FutureTech 變種冠狀病毒蛋白晶片:疫情與後疫情時代之應用

      Due to the recent outbreak of COVID-19ongoing mutants, we developed a coronavirus variant protein microarray that includes all the current spike mutationsthe wild-type viral antigensapplied in detecting immune responsesdrug specificities. We filed the patientspublished our findings in the Analytical Chemistry. Besides massive production of the coronavirus protein microarray, we also collaborated with a scanner company, developed artificial intelligence software,collaborated with suppliers. We are welcome any sort of collaboration.
    • 5D智慧城市─SmartES平台

      AI & IOT Application FutureTech 5D智慧城市─SmartES平台

      NCREE has originally developed 5D digital space—on the basis of 3D city modelsconnections of different kinds of sensors around the world— is an online to offline virtual space with a combination of rising 5G technology advantages. Collectingreorganizing various 3D cartographic data with Building Information Modeling (BIM), satellite imagery, UAV 3D modeling, LiDar point cloud data, etc., can increase the diversity of the buildinglandscape. 5D+5G smart city platform would accelerate the 5D smart city to become the digital twin of a real city.
    • 豬生殖與呼吸綜合症病毒重組結構抗原的應用

      FutureTech 豬生殖與呼吸綜合症病毒重組結構抗原的應用

      PRRSV recombinant antigen A1 inhibits the expression of CD163 on the cell surface by inducing the polarization of M1 macrophage subset, which can further effectively reduce virus invasionreduce infection. A1 can regulate the endogenous genes of alveolar macrophages to activate Th1-type immune responseenhance cellular immunity. Therefore, this technical invention will be beneficial to screen the new generation of PSSRV candidate structural vaccines.
    • 雙重增強表面增強拉曼散射感測器的超靈敏和快速檢測COVID-19 病毒

      FutureTech 雙重增強表面增強拉曼散射感測器的超靈敏和快速檢測COVID-19 病毒

      PCR, a gold-standard diagnostic method, were labor-intensive, time-consuming,costly, which restricted its application to widespread screening. Herein, this study purposes a one-potnon-washing method to rapidly detect virus by dual-SERS mechanism. COVID Antigens were captured by SERS nanoparticlesnovel SERS substrate simultaneously to achieve 6 order enhancements within 20 minutes. The dual-SERS sensors have reached a detection limit of 1 ng/ml in clinical samples for recognizing nucleocapsid & Spike proteins of COVID-19, which is comparable with PCR results.
    • Influenza mucosal vaccine compositionpreparationapplication thereof

      Precision Health Ecosystem FutureTech Influenza mucosal vaccine compositionpreparationapplication thereof

      Provided is an influenza mucosal vaccine compositionpreparationapplication thereof. This composition contains an antigen fusion protein which includes an influenza virus antigena Type IIb heat-labile enterotoxin A subunit. Immunization with the antigen fusion protein induces cellularhumoral immune responses, including systemicmucosal immune responses, against a specific in
    • RSV VACCINE COMPOSITION COMPRISING HEPATITIS B VIRUS-LIKE PARTICLES AS ADJUVANT

      Bio-tech & New Drugs FutureTech RSV VACCINE COMPOSITION COMPRISING HEPATITIS B VIRUS-LIKE PARTICLES AS ADJUVANT

      In this project, we have reorganized several highly immunogenic sitesstructurally essential regions to maintain it in a pre-fusion stateuse it as main antigen in our RSV vaccine candidate (RSV-F005). To induce a mucosal immune response, intranasal administration route was chosen. New mucosal adjuvant (H-muad) has been tested in threee animal models.
    • Low-dose nanoscale biomimetic cell structure – Next-generation platform technology for advanced precision immunotherapy

      Precision Health Ecosystem FutureTech Low-dose nanoscale biomimetic cell structure – Next-generation platform technology for advanced precision immunotherapy

      We developed a biomimetic triple-antibody-immobilized magnetic fucoidan nanomedicine as a multifunctional artificial antigen presenting cell, which possessed the ability to not only inhibit immune checkpoint but activate tumor infiltrated T cells. of Bridging sites with tunable density on the nanoplatform was designed, allowing the antibodies to be well-distributed on the surface for mimicking immune cells. In contrast to the complex cell expansion process using microbeads in adaptive cell therapy, the nanoplatform can be i.v. administrated to cut the course of therapy from several weeks to days. With the development of the platform technology, an artificial immune system family can be built to pave the way for personalized immunotherapy.
    • 免疫組織化學染色肝臟切片量化分析

      FutureTech 免疫組織化學染色肝臟切片量化分析

      "The IHC staining intensity grading algorithm combines a series of complementary processes of deep learningimage processing in order to overcome the difficulties in cell boundary segmentationgrade definition,provides a cell-based IHC staining intensity gradingquantification capability. The proposed method serves as a useful assistive tool for physicians in performing accurate staining quantification in tissue microscopic images. In addition, it analyzes panoramic pathological images in order to determine the factors most strongly associated with likely disease recurrence."