Technical Name A Manual CentrifugePaper Devices for Point-of-Care Diagnosis
Project Operator National Taiwan University
Project Host 陳建甫
Summary Here, we introduce an electricity-free centrifuge platform based on a manual centrifuge. The provided centrifugal force is sufficient to produce a plasma purity of 99 separated in as little as 2−3 min. We then performed an immunoassay on a paper devicethe results were observed by a portable reader. As a result, the detection limit of the C-Reactive Protein is 1 ng/mL, with a total turnaround time of 7 min.
Scientific Breakthrough Here, we introduce an easyelectricity-free centrifuge platform based on a manual centrifuge. The provided centrifugal force is sufficient to produce a plasma purity of 99 separated in 2−3 min. The plasma can then be testedanalyzed using a paper devicea portable reader at the point of need.
Industrial Applicability We expected these techniques can be used for the applications of personalized medicineprecision medicine.
Keyword Blood plasma separation Disease detection paper Portable colorimetric reader Microfluidics Biosensor In vitro diagnosis Chemical Sensor Medical device Precision medicine Personalized medicine
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