| Technical Name |
Multivalent adenoviral vector-based vaccine against hand-food-mouth disease |
| Project Operator |
National Health Research Institutes |
| Project Host |
周彥宏 |
| Inventor |
周彥宏
莊再成
鄒岳良
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| Summary |
We developed a recombinant adenovirus Ad-HFMD vaccine which can express virus-like particles (VLPs) of EV71 capsid proteins. Mouse studies showed that Ad-HFMD can induce the protective antibodycellular immunity against EV71CVA16 in hSCARB2 transgenic (hSCARB2-Tg) mouse challenge model.
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| Market Potential Analysis |
目前研發的FI-EV71疫苗:只能針對腸病毒71型,對克沙奇病毒無效。市場尚無類似多價疫苗產品，因此對於預防腸病毒71型及克沙奇病毒引起的手足口病的市場潛力很大。
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| Industrial Applicability |
1.Ad-HFMD as a multivalent vaccine against EV71CVs-induced hand-food-mouth-disease2.Route of Ad-HFMD immunization are multiple including intranasal, musclesubcutaneous injection to induce anti-EV71CV immunity.
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| Technical Film |
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